Generally speaking, the program can be used, however, some features are not compatible.

Incompatible Features

• Ramp/Curve setting for MIDI CC data (Cubase 11)

Moreover, there is currently a bug with the Mac version that causes some keyboard shortcuts to not work properly.

Furthermore, no problems have been found with using the VOCALOID5 VST or VOCALOID5 AU versions with Cubase 10, Cubase 10.5 or Cubase 11, so we recommend that you use one of those.